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目的探讨供精人工授精的两种不同方式对周期妊娠的影响。方法根据AID方式不同,将822例AID周期样本分为宫腔内人工授精(intrauterine insemination, IUI)组(304例)和宫颈内人工授精(intracervical insemination, ICI)组(518例),并比较两组的妊娠结局。结果 IUI组的临床妊娠率高于ICI组(26.3%~19.5%,<0.05)。而两组间活产婴儿率与流产率无显著差异。结论 IUI相比ICI可以获得更高的周期妊娠率,对于临床上AID人工授精方式的选择具有一定的参考意义。“,”Objective To investigate the relationship between two different methods of AID and clinical outcome. Methods A total of 822 AID cycles were divided to two groups:group A(IUI) and group B(ICI), and compare the clinical outcome between the two groups. Results The pregnancy rate in group A was significantly higher than that in group B(26.3%~19.5%, <0.05). Nevertheless, no relationship was found between the two group in live-birth rate or miscarriage rate. Conclusion Patients undergoing IUI may get higher clinical pregnancy rate compared with ICI, which may provide certain reference significance for clinical therapy strategy.