脑卒中的发病率在全世界范围内不断增加[1]。在我们国家,脑卒中是导致死亡的主要原因之一。缺血性卒中再灌注后形成二次损伤,脑内含水量迅速增加,导致脑体积增大,颅内压升高,使缺血卒中的危险性增高[2]。研究发现,水通道蛋白家族对脑水肿的形成发展有重要的作用。缺血再灌注发生后,水通道蛋白AQP-1的含量显著增加,促进脑微血管的通透性,对脑水肿的形成、发展有重要作用[3]。中国的传统医学认为,中风与风火痰淤相关。中风发生 The incidence of stroke is increasing throughout the world [1]. Stroke is one of the leading causes of death in our country. Secondary ischemia is formed after reperfusion of ischemic stroke, and the water content in the brain increases rapidly, resulting in an increase of brain volume and an increase of intracranial pressure, which increases the risk of ischemic stroke [2]. The study found that aquaporin family of brain edema formation and development has an important role. After ischemia-reperfusion, the content of aquaporin AQP-1 is significantly increased and the permeability of cerebral microvascular is promoted, which plays an important role in the formation and development of cerebral edema [3]. Chinese traditional medicine believes that stroke and phlegm stasis related. Stroke occurs