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本文着重对神经递质和调质等与运动性中枢疲劳的关系及其作用机制的研究进展进行了分析,5-HT、DA、胆碱和乙酰胆碱、氨基酸类递质是引起运动性中枢疲劳的物质。研究结果显示,5-HT是影响中枢系统疲劳的抑制性递质,但它的影响效果与训练强度和部位有关;脑中多巴胺可能通过抑制了5-HT的合成与代谢,从而推迟运动性中枢疲劳的发生;服用胆碱饮料能推迟疲劳的发生,但影响机制尚待研究;具有兴奋性作用的氨基酸类递质主要有谷氨酸和天冬氨酸,抑制性作用的有r-氨基丁酸。属神经调质类的氨和细胞素的增高可导致中枢神经系统产生疲劳。
This article focuses on the neurotransmitter and quenching and exercise central fatigue and the relationship between the mechanism of action is analyzed, 5-HT, DA, choline and acetylcholine, amino acid neurotransmitter is caused by exercise-induced central fatigue substance. The results showed that 5-HT is an inhibitory neurotransmitter that affects central nervous system fatigue, but its effect is related to training intensity and location. Brain dopamine may delay the synthesis of 5-HT and metabolism, Fatigue occurs; take choline drinks can delay the occurrence of fatigue, but the mechanism of action yet to be studied; with excitatory amino acids mainly glutamate and aspartate, inhibitory effect of r-aminobutyl acid. Elevated levels of ammonia and cytokines, which are neurotransmitters, can lead to central nervous system fatigue.