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作者为了了解感染棉鼠丝虫的棉鼠和沙鼠用海群生治疗后出现不同抗丝虫作用的原因,比较了两种动物的单核吞噬细胞系的活性。先给8周龄的雄性棉鼠和沙鼠感染20条棉鼠丝虫感染期幼虫,每组4～6鼠,感染后12周腹腔内一次注射海群生(DEC)100mg/kg,在治疗前、后定量查尾血作微丝蚴计数;另用8周龄的动物进行单核吞噬细胞系活性的比较,在鼠的阴茎背静脉分别注入5、10、
The authors compared the activity of mononuclear phagocytic cell lines in both animals in order to understand the reasons for the different antifungi effects of cotton bollworms and gerbil treated with sea buckthorn in infected cotton ticks. Eighty-week-old male cotton rats and gerbils were infected with 20 infective larvae of cotton ticks (4 to 6 mice per group). One week after the injection, 100 mg / kg of DEC was injected intraperitoneally. Before treatment, After the quantitative tail fin blood for microfilariae count; the other 8 weeks old animals mononuclear phagocytic cell line activity comparison, respectively, injected into the penis dorsal vein 5,10,