论文部分内容阅读
答:有的同志提出,安他唑啉(antistin:安替司丁;安他心)在《临床药理20讲》一书47页写道,该药既有抗胆碱作用,又有抗肾上腺素作用,对此难以理解。其实,任何一种药物,随着剂量的变化,作用可以是多方面的。双重性是一系列药物的共性。例如安他唑啉既有抗组胺作用,而对人和豚鼠肺,又有释放组胺作用,引起支气管收缩[参见 AlivisatosSGA et al:Handbuch der ExperimentellenPharmakologie(part Ⅰ),p 585,1966];β-受体阻滞剂可阻滞心脏β-受体而表现抑制心脏收缩力和传导,但它们又有内在性儿茶酚胺活性,从而可增强心脏收缩力和加速传导;地塞米松有抗过敏作用,但本
A: Some comrades suggested that antistin (antiinfective; antihistamine) wrote on page 47 of “Clinical Pharmacology” that the drug has anticholinergic effects as well as anti-adrenal Supra, which is difficult to understand. In fact, any kind of medicine, with the dose changes, the role can be multifaceted. Duality is the commonality of a series of medicines. For example, anti-histamine effects of both anti-histamine effects and release of histamine on human and guinea pig lungs cause bronchoconstriction [see Alivisatos SGA et al: Handbuch der Experimentellen Pharmakologie (part I), p 585, 1966] - Receptor blockers block the heart’s beta-receptors and appear to inhibit cardiac contractility and conduction, but they have an intrinsic catecholaminergic activity that enhances cardiac contractility and accelerates conduction; dexamethasone has an anti-allergic effect, But this