论文部分内容阅读
目的评价硬膜外吗啡复合氟哌利多单次注入对小儿术后镇痛的效果及安全性。方法选择择期腹部或下肢手术的患儿60例,随机分为A、B、C 3组,术毕A组硬膜外注入吗啡0.04～0.05mg/kg加入0.9%氯化钠10 ml,B组硬膜外给予吗啡0.04～0.05 mg/kg和氟哌利多0.03 mg/kg加入0.9%氯化钠10 ml,C组硬膜外给予吗啡负荷量20μg/kg后,以维持量2μg·kg~(-1)·h~(-1)持续注入,观察镇痛效果及副作用,术中监测血压、心率、呼吸频率及脉搏氧饱和度。结果3组间镇痛评分无统计学差异,但B组复合氟哌利多不良反应明显减少。结论硬膜外吗啡0.04～0.05 mg/kg复合氟哌利多0.03 mg/kg加入0.9%氯化钠10 ml单次注入是小儿术后简单、实用而又安全有效的镇痛方法之一。
Objective To evaluate the efficacy and safety of epidural morphine combined with droperidol single injection on postoperative analgesia in children. Methods Sixty children with elective abdominal or lower limb surgery were randomly divided into A, B and C groups. A group received epidural injection of morphine 0.04-0.05 mg / kg in 10% 0.9% sodium chloride solution after operation, and group B Epidural morphine 0.04-0.05 mg / kg and droperidol 0.03 mg / kg were added 0.9% sodium chloride 10 ml, group C, epidural morphine loading 20μg / kg, the maintenance dose 2μg · kg ~ ( -1) · h ~ (-1). The analgesic effects and side effects were observed. The intraoperative blood pressure, heart rate, respiratory rate and pulse oxygen saturation were monitored. Results There was no significant difference in analgesic scores among the three groups, but the side effects of compound droperidol in group B were significantly reduced. Conclusions Single injection of epidural morphine 0.04-0.05 mg / kg combined with droperidol 0.03 mg / kg and 0.9% sodium chloride 10 ml is one of the simple, practical and safe analgesic methods after pediatric operation.