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作者对３３例宫颈癌患者的活检组织进行了ＤＮＡ含量和ＨＰＶ１６检测。结果显示：宫颈癌细胞ＤＮＡ异倍体率为６６．７％，ＨＰＶ１６阳性率３３．３％。异倍体患者ＨＰＶ１６阳性率显著高于二倍体患者（Ｐ＜０．０５）；在异倍体病例中，不同倍体类型者ＨＰＶ１６阳性率明显不同，其顺序为多异倍体＞非整倍体＞四倍体＞近二倍体。ＨＰＶ１６阳性者的ＤＩ、ＳＰＦ、＞２Ｃ％均显著高于ＨＰＶ１６阴性者（Ｐ＜０．０１）。该结果提示，ＨＰＶ１６不仅与宫颈癌的发生关系密切，而且和癌细胞ＤＮＡ含量、增植特性、肿瘤恶性度也有一定关系。
The authors performed DNA content and HPV16 detection on biopsies of 33 patients with cervical cancer. The results showed that the DNA aneuploidy rate of cervical cancer cells was 66.7% and the positive rate of HPV16 was 33.3%. The positive rate of HPV16 in aneuploid patients was significantly higher than that in diploid patients (P <0.05). In aneuploid cases, the positive rates of HPV16 in different ploidy types were significantly different, the order of which was poly aneuploidy> non-whole Diploid> Tetraploid> Near diploid. DI, SPF,> 2C% of HPV16 positive patients were significantly higher than that of HPV16 negative patients (P <0.01). The results suggest that HPV16 is not only closely related to the occurrence of cervical cancer, but also has a certain relationship with the DNA content, growth characteristics and tumor malignancy of cancer cells.