注射剂中可能含有一些外源性粒子,其大小(0.5～30μm)为胶体粒子范围或稍大些。药典上规定了微粒污染的限度。输液中存在粒子,一般认为有危险性。某些污染与引起肿瘤有联系。与此相反,有些静脉注射剂,例如诊断用放射性微粒制剂等,可以特意含有成百万个微粒。可降解的微球用作静注或动脉注射药物的给药系统,如抗肿瘤药载体。 Injection may contain some exogenous particles, the size (0.5 ~ 30μm) colloidal particle range or slightly larger. Pharmacopoeia states the limits of particulate contamination. There are particles in the infusion, generally considered to be dangerous. Some of the pollution associated with causing tumors. In contrast, some intravenous injections, such as diagnostic radioactive nanoparticle formulations and the like, can specifically contain millions of microparticles. Biodegradable microspheres are used as drug delivery systems for intravenous or intra-arterial injections of drugs, such as anti-tumor drug carriers.