氮斯丁(Azelastine)是一类新的化台物,具有抗炎、平喘、抗变态反应等多种药理作用。有研究发现,联合氮斯丁治疗哮喘可减少其它平喘药物如茶碱和β受体激动剂的用量,而不影响症状的控制。理论上,氮斯丁亦可减少激素的用量。为此,作者评价了口服氮斯丁对慢性中～重度哮喘患者吸入激素的减量作用。 对象 选择年龄12～73岁的慢性中～重度哮喘 Azelastine (Azelastine) is a new class of compounds, with anti-inflammatory, antiasthmatic, anti-allergic reactions and other pharmacological effects. Studies have found that combined with azathisin in the treatment of asthma can reduce the other antiasthmatic drugs such as theophylline and β-agonist dosage, without affecting the control of symptoms. In theory, nitrogen ostine can also reduce the amount of hormones. To this end, the authors evaluated the reductions of inhaled corticosteroids by oral azathisin in patients with chronic moderate-to-severe asthma. Subjects Chronic moderate-to-severe asthma aged 12-73 years was selected