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目的：评价西拉普利的降压疗效及对心率、血脂、血糖、血钾、肌酐、GPT的影响。方法：30例高血压患者采用随机、单盲、安慰剂治疗前后自身对照试验法。给予西拉普利2．5mg，每日一次，每周末测血压心率，服药共4周，在治疗前后分别进行血脂、血糖、血钾、肌酐、GPT的检查。结果：服药后降压总有效率在一周末为80％，两周末为89．7％，三周末为89．7％，四周末为83．3％，而对心率、血脂、血糖、血钾、肌酐、GPT的影响无统计学意义（P＞0．05）。结论：西拉普利是安全有效的降压药，且对心率、血脂、血糖、血钾、肌酐、GPT无明显的影响。
OBJECTIVE: To evaluate the antihypertensive effects of cilazapril and its effects on heart rate, blood lipid, blood glucose, serum potassium, creatinine and GPT. Methods: Thirty patients with hypertension were randomized, single-blind, placebo-controlled self-control test. Give Cilazapril 2.5mg, once daily, blood pressure heart rate every weekend, taking a total of 4 weeks, respectively, before and after treatment of blood lipids, blood glucose, serum potassium, creatinine, GPT examination. Results: The total effective rate of antihypertensive medication was 80% at one week, 89.7% at two weeks, 89.7% at three weeks and 83.3% at the end of the four weeks. The heart rate, blood lipid, blood glucose, potassium , Creatinine, GPT had no statistical significance (P> 0.05). Conclusion: Cilazapril is a safe and effective antihypertensive drug, and has no obvious effect on heart rate, blood lipid, blood glucose, serum potassium, creatinine and GPT.