抗凝血酶Ⅲ(AntitbrombinⅢ),简写为AT-Ⅲ)是血浆中凝血酶,因子X_(?)等丝氨酸蛋白酶类的主要生理性抑制剂,AT-Ⅲ的缺乏可导致血液高凝和血栓栓塞性疾病。自Egcberg于1965年在挪威报导第一例遗传性AT-Ⅲ缺乏症引起血栓形成体质(Thrombophilia)的病人和家族以来,世界上很多国 Antitromobin Ⅲ (AT-Ⅲ for short) is a major physiological inhibitor of serine proteases such as thrombin and cytokines in plasma. The lack of AT-Ⅲ leads to hypercoagulability and thromboembolism Sexually transmitted diseases. Since Egcberg reported in Norway in 1965 that the first case of familial AT-III deficiency caused Thrombophilia in patients and families, many countries in the world