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一、鼻咽癌癌前病变的提出 1970年对中山县10岁以上10万人进行肿瘤普查,检出鼻咽癌患病率为109.5/10万,发现鼻咽非癌性病变179例,在临床上主要表现为增生结节,成年人腺样体增殖和粘膜重度慢性炎症。稍后,包括上述10万人口在内,对中山县242,757人(10岁以上)进行鼻咽检查,也发现555例鼻咽上皮增生性病变。对其中307例作了活检,33例确诊为Ⅰ期鼻咽癌。进一步结合本省廉江、揭阳二县及汕头市的普查资料,包括中山县在内共436,786人进行分析,发现高发区中山县居民鼻咽粘膜上皮增生的比例为228.6/10万人口,高于低发区汕头市,揭阳县及廉江县(155.1/10万)。并
First, advance the precancerous lesions of nasopharyngeal carcinoma 1970 to 10 years old 100,000 people in Zhongshan County tumor screening, detection of nasopharyngeal cancer prevalence was 109.5/10 million, found 179 cases of nasopharyngeal non-cancerous lesions, in The main clinical manifestations are hyperplastic nodules, adult adenoids proliferation and severe chronic mucosal inflammation. Later, including the above-mentioned population of 100,000, 242,757 people (10 years old or older) in Zhongshan County were examined by nasopharyngeal examination and 555 cases of nasopharyngeal epithelial hyperplasia were also found. Of these, 307 cases were biopsied and 33 were diagnosed as stage I nasopharyngeal carcinoma. By further integrating the census data of the provinces of Lianjiang, Jieyang, and Shantou, including 436,786 people in Zhongshan County, it was found that the proportion of nasopharyngeal epithelial hyperplasia in residents of the high incidence area Zhongshan County was 228.6 per 100,000 population, which was higher than The districts of Shantou City, Jieyang County and Lianjiang County (155.1/10 million). and