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近年来,肢端肥大症与恶性肿瘤间的联系已引起重视,作者在48例肢端肥大症病例中搜集胃肠道肿瘤的资料作一回顾性研究。 作者在1976—1981年间复习肢端肥大症48例资料,年龄30—80岁,平均61岁,男23例,女25例,患胃肠癌5例,其中胃癌2例,结肠癌2例,直肠癌1例,在1例胃癌和1例乙状结肠癌病人曾患复发性结肠息肉。另有2例患乳腺癌。饶有兴趣地注意到:1.在男性患胃癌,女性患结肠癌的危险性明显增高,另外乳腺癌的危险性也被注意到。2.5例胃肠癌病人中,2例在诊断痛肿后第11年和第16年出现肢端肥大症;3例在诊断肢端肥大症后第13—16年间出现胃肠肿瘤。五例病人在癌肿诊断后平均存活10年。
In recent years, the connection between acromegaly and malignant tumors has attracted attention. The authors conducted a retrospective study of the collection of gastrointestinal tumors in 48 cases of acromegaly. The authors reviewed data on 48 cases of acromegaly from 1976 to 1981, aged 30-80 years, with an average age of 61 years, 23 males and 25 females. There were 5 cases of gastrointestinal cancer, including 2 cases of gastric cancer and 2 cases of colon cancer. One case of rectal cancer had recurrent colon polyps in one patient with gastric cancer and one patient with sigmoid colon cancer. Another 2 cases had breast cancer. Interestedly noted: 1. In men suffering from gastric cancer, the risk of colon cancer is significantly higher in women, and the risk of breast cancer is also noticed. Of 2.5 patients with gastrointestinal cancer, 2 had acromegaly in the 11th and 16th years after diagnosis of pain and swelling, and 3 had gastrointestinal tumors in the 13th to 16th years after diagnosis of acromegaly. Five patients survived an average of 10 years after diagnosis of cancer.