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四物汤５ｇ／ｋｇｉｐ能显著对抗利多卡因的毒性，并增加大鼠对利多卡因的耐受量；１．７ｇ／ｋｇｉｖ能降低利多卡因中毒小鼠的死亡率。
Siwu Decoction 5g/kgip significantly against the toxicity of lidocaine, and increase the tolerance of rats to lidocaine; 1.7g/kgiv can reduce the mortality of lidocaine poisoning mice.