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目的探讨逆行保留灌肠法联合实时超声造影诊断结肠病变的临床价值。方法选取2013年10月至2015年2月东莞市清溪医院收治的50例结肠病变患者作为研究对象,28例为恶性病灶组,22例为良性病灶组。选择同期健康检查无结肠病变的体检者30例作为对照组。所有受检对象均行逆行保留灌肠法联合实时超声造影检查,比较3组受检对象定量参数到达时间、达峰时间、上升时间、基础强度、峰值强度及强度相对值。结果恶性病灶组受检对象峰值强度、强度相对值均明显高于对照组以及良性病灶组,到达时间、达峰时间均明显短于对照组以及良性病灶组,差异均有统计学意义(均P<0.05);同时,良性病灶组受检对象峰值强度、强度相对值均明显高于对照组,到达时间、达峰时间均明显短于对照组,差异均有统计学意义(均P<0.05)。结论逆行保留灌肠法联合实时超声造影能够准确区别正常结肠组织与病变组织,同时可对病灶良恶性作出较可靠鉴别,在结肠病变的临床诊断中具有重要价值。
Objective To investigate the clinical value of retrograde retention enema in combination with real-time contrast-enhanced ultrasound in the diagnosis of colonic lesions. Methods Fifty patients with colonic lesions treated at Qingxi Hospital of Dongguan City from October 2013 to February 2015 were selected as the study subjects, 28 patients with malignant lesions and 22 patients with benign lesions. Select the same period of health examination without colorectal disease in 30 cases as a control group. All subjects underwent retrograde retention enema combined with real-time contrast-enhanced ultrasound contrast, the measured parameters of the three groups were compared the arrival time, peak time, rise time, basal intensity, peak intensity and relative intensity. Results The peak intensity and the relative strength of the subjects in the malignant group were significantly higher than those in the control group and the benign group, the time of arrival and peak time were significantly shorter than those in the control group and the benign group (P <0.05) <0.05). At the same time, the peak intensity and the relative intensity of the subjects in the benign lesion group were significantly higher than those in the control group, the time of arrival and peak time were significantly shorter than those of the control group (all P <0.05) . Conclusion Retrograde retention enema combined with real-time contrast-enhanced ultrasound can accurately distinguish normal colorectal tissues from diseased tissues. At the same time, it can make a reliable identification of benign and malignant lesions, which is of great value in the clinical diagnosis of colonic lesions.