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目的:观察二半汤临床控制老年2型糖尿病患者血糖的效果。方法:选取2013年1~12月本院新诊248例老年2型糖尿病患者病例,随机分为2组,各124例。对照组以二甲双胍治疗,观察组在对照组基础上联用二半汤治疗。比较2组患者临床疗效、血糖指标、胰岛功能指标。结果:经3月治疗,观察组治疗总有效率为94.4%,高于对照组的79.8%,2组比较,差异有显著性意义(P<0.05)。治疗后2组空腹血糖(FBG)、餐后2h血糖(P2hBG)和糖化血红蛋白(HbA1c)显著改善(P<0.05),观察组各指标水平明显优于对照组(P<0.05)。治疗后2组患者空腹胰岛素(FINS)、空腹C肽(FCP)、胰岛素抵抗水平指标(HOMA-IR)、胰岛β细胞分泌功能指标(HOMA-β)明显改善(P<0.05);观察组胰岛功能显著优于对照组(P<0.05)。结论:二半汤联合二甲双胍能有效控制老年2型糖尿病患者的血糖,疗效显著,值得推广。
Objective: To observe the effect of two half-soup on controlling blood glucose in elderly patients with type 2 diabetes mellitus. Methods: A total of 248 elderly patients with type 2 diabetes mellitus admitted to our hospital from January to December in 2013 were selected and randomly divided into two groups (124 cases each). The control group was treated with metformin. The observation group was treated with two half-soup on the basis of the control group. The clinical efficacy, blood glucose and islet function were compared between the two groups. Results: After treatment in March, the total effective rate of the observation group was 94.4%, which was higher than that of the control group (79.8%). There was significant difference between the two groups (P <0.05). After treatment, FBG, P2hBG and HbA1c in two groups were significantly improved (P <0.05), and the indexes in the observation group were significantly better than those in the control group (P <0.05). The levels of fasting insulin (FINS), fasting C-peptide (FCP), insulin resistance (HOMA-IR) and the secretion of HOMA-β in the two groups were significantly improved after treatment (P < Function was significantly better than the control group (P <0.05). Conclusion: Two half-soup combined with metformin can effectively control the elderly with type 2 diabetes, blood glucose, significant effect, it is worth promoting.