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采用大蒜素、川芎嗪、小檗胺对野百合碱诱发大鼠肺动脉高压并进行降压治疗，观察了降压前后肺血管功能、形态与肺动脉高压的关系。结果表明，肺血管功能形态改变与肺动脉高压密切相关，其中以大蒜素的降压作用最佳，并对其发病机制进行了探讨。
The effects of allicin, ligustrazine and berbamine on monocrotaline-induced pulmonary hypertension in rats were observed. The pulmonary vascular function and morphology before and after blood pressure reduction were observed. The results showed that pulmonary vascular changes in morphology and pulmonary hypertension are closely related to all the antihypertensive effect of allicin best, and its pathogenesis were discussed.