论文部分内容阅读
脏器移植的最大障碍是移植器官无功能,79％的移植肾无功能由于排异反应,约50％尸体肾的功能仅维持1年。近年来肾移植受体生存率明显提高,而移植肾生存率并无明显改善,主要由于未能防止移植肾无功能。一、HLA配型:移植肾无功能被认为由于免疫反应的结果(即排异反应),生物学基础是先天性差异,是否发生排异取决于供体及受体间的血缘关
The biggest obstacle to organ transplantation is that there is no function in transplanted organs and no function in 79% of transplant kidneys. Due to rejection, the function of about 50% of cadaveric kidneys is only maintained for 1 year. In recent years, the survival rate of renal transplant recipients increased significantly, while no significant improvement in the survival rate of renal allografts, mainly due to failed to prevent graft non-functional. First, the HLA matching: No function of the kidney graft is considered as a result of the immune response (ie rejection), the biological basis of congenital differences in whether the rejection occurs depends on the blood donor and receptor