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目的 探讨盆腔区域性动脉化疗配合手术治疗膀胱癌的方法与效果。方法 应用小剂量顺铂盆腔区域性动脉化疗配合手术治疗膀胱癌 5 4例 ,其中术前动脉化疗 41例 ,术后动脉化疗 13例。对术前动脉化疗的 41例进行术中肿瘤大体观察及术后病理组织学光镜下观察 ,并对全部病例进行术后疗效追踪观察。结果 动脉化疗总有效率为 85 %。术后随访 0 .5～ 10年 ,复发率为 36 %。结论 盆腔区域性动脉化疗配合手术 ,能够有效控制和减少膀胱癌术后复发 ,延长术后膀胱无瘤期 ,提高生存率。
Objective To investigate the method and effect of pelvic regional arterial chemotherapy combined with surgical treatment of bladder cancer. Methods Low-dose cisplatin-pelvic regional arterial chemotherapy was used in combination with surgery for bladder cancer in 54 patients, of which 41 were preoperative arterial chemotherapy and 13 postoperative arterial chemotherapy. 41 cases of preoperative arterial chemotherapy were performed to observe the tumor during operation and the histopathology under the light microscope. All the cases were followed up. Results The total effective rate of arterial chemotherapy was 85%. After follow-up of 0.5 to 10 years, the recurrence rate was 36%. Conclusion Pelvic regional arterial chemotherapy combined with surgery can effectively control and reduce postoperative recurrence of bladder cancer, prolong postoperative bladder-free period, and improve survival rate.