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对1979年7月至1996年6月的突发性聋(突聋)发病情况进行前瞻性研究与回顾性分析,探讨突聋与铁代谢障碍疾病的关系。前瞻性研究的对象分为铁代谢障碍疾病组218例、血液病组215例和正常对照组4850例;回顾性分析为17年间资料完整的429例突聋患者中铁代谢障碍疾病及其他血液病的发病情况。结果表明,铁代谢障碍疾病组的突聋调整年发病率显著高于血液病组以及正常对照组;429树突聋患者的无贫血缺铁、缺铁性贫血总检出率为60.84%。认为,机体铁代谢障碍不等于耳蜗铁代谢障碍,但机体铁代谢障碍时出现耳蜗铁代谢障碍的机率显著增加,在许多情况下,耳蜗急性铁代谢障碍是突聋的直接或间接病因之一。
From July 1979 to June 1996, the incidence of sudden deafness (sudden deafness) was prospectively studied and retrospectively analyzed to explore the relationship between sudden deafness and iron metabolism disorders. The prospective study was divided into 218 patients with iron metabolism disorder disease group, 215 patients with hematological disease group and 4850 normal control group; retrospective analysis of 17 years of complete data of 429 cases of sudden deafness in patients with iron metabolism disorders and other blood diseases Incidence. The results showed that the incidence of sudden deafness in the group with iron metabolism disorder was significantly higher than that in the hematological disease group and the normal control group. The total detection rate of iron deficiency anemia without anemia in 429 dendritic patients was 60.84% . It is considered that the iron metabolism disorder of the body is not equal to the iron metabolism disorder of the cochlea, but the incidence of iron metabolism disorder of the cochlea is significantly increased when the iron metabolism disorder of the body occurs. In many cases, the acute iron metabolism disorder of the cochlea is one of the direct or indirect causes of sudden deafness.