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癫痫是一种常见病,目前仍以药物治疗为主,故寻找新的有效的抗癫痫药和其作用机制的研究是医药学研究的主要课题之一。近年来随着科学的进展,除发现了一些新的抗癫痫药外,对于临床多年来广泛应用的药物作用机制也进行了广泛深入的研究,例如对于苯妥英钠和苯巴此妥的作用机制研究,取得了很大进展,这方面已有综述,本文仅就抗癫痫药物与GABA的关系方面综述。
Epilepsy is a common disease and is still mainly treated with drugs. Therefore, finding new and effective antiepileptic drugs and their mechanism of action is one of the major topics in medical research. In recent years, with the progress of science, in addition to discovering some new antiepileptic drugs, extensive and in-depth research has been conducted on the mechanism of action of drugs widely used for many years in clinical practice. For example, the mechanism of action of phenytoin sodium and phenobarbital , Has made great progress, this area has been reviewed, this article only on the anti-epileptic drugs and GABA relationship review.