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目的对儿童吸入七氟烷后躁动症状使用右美托咪定进行治疗的临床效果进行探讨分析。方法此次研究的对象是选取2013年2月到2014年8月我院手术室收治的68例因吸入七氟烷全身麻醉的儿童,随机分为试验组和对照组,每组34例。试验组在手术结束前30 min给予右美托咪啶静脉推注,对照组给予相同剂量的0.9%氯化钠注射液静脉推注,观察比较两组患儿手术后的苏醒时间以及躁动情况。结果两组患儿在用药前后的心率(HR)、平均动脉压(MAP)、脉氧饱和度(Sp O_2)和呼气末二氧化碳分压(PETCO_2)等基本指标没有统计学差异性(P>0.05);两组患儿的临床苏醒时间无统计学差异性(P>0.05);研究组比对照组躁动表现要轻微些,存在统计学差异性(P>0.05)。结论右美托咪啶能够预防儿童吸入七氟烷全身麻醉后的躁动不安状况,临床疗效较佳,值得在临床上推广应用。
Objective To investigate the clinical effect of using dexmedetomidine to treat restless symptoms of sevoflurane inhalation in children. Methods The object of this study was to select 68 children admitted to the operating room of our hospital from February 2013 to August 2014 for sevoflurane inhalation. They were randomly divided into experimental group and control group with 34 cases in each group. The experimental group was given intravenous injection of dexmedetomidine 30 min before the end of surgery, and the control group was given the same dose of 0.9% sodium chloride injection intravenously. The recovery time and agitation of the two groups were observed and compared. Results There were no significant differences in HR, MAP, Sp O 2 and PETCO 2 between the two groups before and after treatment (P> 0.05). There was no significant difference in clinical recovery time between the two groups (P> 0.05). The agitation performance of the study group was slightly lower than that of the control group (P> 0.05). Conclusion Dexmedetomidine can prevent restlessness after inhalation of sevoflurane in children. The clinical effect is better and it is worth to be popularized in clinic.