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选用自由基代谢为指标，对比观察了补肾六味地黄汤、化瘀丹坤方及补肾化瘀六味丹坤方的延缓衰老作用。实验结果表明：（１）六味地黄汤及丹坤方均能明显增加老年小鼠红细胞ＣＡＴ的活性，增加ＮＰＳＨ的含量，减少肝脑ＭＤＡ含量，即明显改善老年小鼠的自由基代谢紊乱；丹坤方尚能明显增强老年小鼠ＳＯＤ及ＧＳＨ－Ｐｘ的活性；（２）补肾化瘀六味丹坤方的作用明显优于单纯补肾的六味地黄汤或单纯化瘀的丹坤方；（３）补肾化瘀是更为有效的延缓衰老手段，并为衰老的“正虚挟瘀”观点提供了实验证据。
Free radical metabolism was chosen as an index to compare and observe the anti-aging effect of kidney-tonifying Liuwei Dihuang Decoction, Huayu Dankun Formula and Bushen Huayu Liuwei Dankun Formula. The experimental results showed that: (1) Liuweidihuang Decoction and Dankunfang can significantly increase CAT activity, increase NPSH content, decrease MDA content in liver and brain, and significantly improve the metabolism disorder of free radicals in senile mice; Kunfang Shang can significantly enhance the activity of SOD and GSH-Px in aged mice; (2) the effect of Bushen Huayu Liuwei Dankun Decoction is obviously better than that of Liuwei Dihuang Decoction or simple Kunzhu Decoction; (3) Stasis is a more effective means of delaying aging and provides experimental evidence for the concept of “being virtual stasis” of aging.