人类T淋巴细胞与绵羊红细胞在适当条件下可形成自然玫瑰花结,该试验已应用于临床,作为检测细胞免疫功能的方法之一。人淋巴细胞也能与小鼠或猴红细胞形成自然玫瑰花结,被认为是B淋巴细胞或其亚群的标志。多种哺乳动物淋巴细胞与异种动物红细胞在试管内也有形成自然玫瑰花结的特性,并可分别表示动物T或B淋巴细胞的免疫功能状态。免疫学研究,诸如疫苗免疫效果的观察,治疗药物对免疫功能的影响和微生物对免疫器官的作用等,往往需要制备适当的动物模型,而这些动物血标本是否能进行自然玫瑰花结试验,以及正常指标如何,也应有 Human T-lymphocytes and sheep erythrocytes can form natural rosettes under appropriate conditions. This test has been used clinically as one of the methods to detect cellular immune function. Human lymphocytes also form natural rosettes with mouse or monkey erythrocytes and are considered markers of B lymphocytes or their subpopulations. A variety of mammalian lymphocytes and heterologous animal red blood cells also have natural rosette characteristics in vitro, and can represent the immune function status of animal T or B lymphocytes, respectively. Immunological studies, such as the observation of the effects of vaccine immunity, the effects of therapeutic drugs on immune function, and the role of microorganisms on immune organs, often require the preparation of appropriate animal models, and whether these animal blood samples can be tested for natural rosettes, and What about normal indicators? There should also be