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目的分析抗结核药物的不良反应发生情况,对不良反应的危害及其处理措施进行评价。方法选取泸州市合江县2015-04-01/2015-09-30登记治疗的223名初治患者进行随访和跟踪调查并进行分析。结果 223例患者中150例患者发生不良反应,总不良反应发生率达67.26%。不良反应类型中,主要为高尿酸血症(46.64%),其次是肝酶升高(13.90%)和皮肤瘙痒(7.17%);不良反应以轻度为主(76%);不良反应发生后,只有8.67%的患者需停用或减量结核药物。发生不良反应的150例患者采取及时有效的处理措施后治疗成功率达100%。结论抗结核药品的不良反应发生率高,但及时采取有效处理措施,患者仍能获得很好的依从性和治疗成功率。
Objective To analyze the adverse reactions of anti-tuberculosis drugs and evaluate the harm of adverse reactions and its treatment measures. Methods A total of 223 untreated patients registered for treatment in Hejiang County, Luzhou City, 2015-04-01 / 2015-09-30 were followed up, followed up and analyzed. Results Of 223 patients, 150 patients had adverse reactions and the total adverse reaction rate was 67.26%. The main types of adverse reactions were hyperuricemia (46.64%), followed by elevated liver enzymes (13.90%) and pruritus (7.17%); mild adverse reactions (76%); adverse reactions , Only 8.67% of patients need to stop or reduce tuberculosis drugs. 150 cases of adverse reactions to take timely and effective treatment measures after the success rate of 100%. Conclusion The incidence of adverse reactions of anti-tuberculosis drugs is high, but in a timely manner to take effective treatment, patients can still get good compliance and treatment success rate.