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噬菌体展示抗体库技术是一种将抗体组合文库与噬菌体表面展示技术相结合所形成的新技术,可以将抗体分子展示在噬菌体表面,且保持了抗体的天然构象和生物学活性,为人源抗体的制备提供了良好的技术平台。本文对噬菌体展示抗体库技术的原理、特点、类型及其研究进展作一综述。
Phage display antibody library technology is a combination of antibody combinatorial library and phage display technology formed by the new technology can be displayed on the phage antibody molecules on the surface and maintain the natural conformation and biological activity of antibodies for human antibody Preparation provides a good technology platform. This article reviews the principle, characteristics, types and progress of phage display antibody library technology.