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目的探讨超敏C反应蛋白(HS-CRP)、血脂(TC、TG、HDL-C、LDL-C)、血尿酸(BUA)、血糖(GLU)、D-二聚体(D-D)水平与冠心病(CHD)的关系。方法对在武汉大学人民医院住院的68例冠心病患者采用荧光免疫干式定量法测定HS-CRP,采用酶比色法测定TC、TG、HDL-C、LDL-C和BUA,采用免疫比浊法测定D-D水平。用SPSS 11.0统计软件对试验数据进行统计分析。结果冠心病患者HS-CRP、TG、GIU、RUA和D-D水平均明显比健康对照组高(P<0.01),HDL-C却比对照组低(P<0.01);LDL-C、TC差异无统计学意义(P>0.05)。结论炎症、高血脂、高血糖和高尿酸血症与冠心病的发生关系密切。
Objective To investigate the relationship between the levels of high-sensitivity C-reactive protein (HS-CRP), blood lipids (TC, TG, HDL-C and LDL-C), blood urea nitrogen (BUA), blood glucose (GLU) and D-dimer Heart disease (CHD) relationship. Methods Sixty-eight patients with CHD who were hospitalized at People’s Hospital of Wuhan University were enrolled in this study. HS-CRP was measured by fluorescence quantitative immunofluorescence assay. The levels of TC, TG, HDL-C, LDL-C and BUA were determined by enzyme-linked immunosorbent assay Determination of DD level. SPSS 11.0 statistical software for statistical analysis of experimental data. Results The levels of HS-CRP, TG, GIU, RUA and DD in CHD patients were significantly higher than those in healthy controls (P <0.01), but HDL-C was lower in CHD patients than in control subjects Statistical significance (P> 0.05). Conclusion Inflammation, hyperlipemia, hyperglycemia and hyperuricemia are closely related to the occurrence of coronary heart disease.