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目的：观查中药治疗对IgA肾病白胞介素10的作用。方法选取IgA肾病患者30例为治疗组，健康人20例为对照组。除高血压患者口服降压（血管紧张素转化酶抑制剂和（或）钙拮抗剂）外，治疗组通过辨证论治给予中药汤剂口服。健康对照组不予任何干预措施。运用流式细胞仪检测治疗组及对照组的外周血白细胞介素10水平并进行比较。结果治疗组与对照组白介素10比较两者存在统计学差异（P＜0．05）；治疗前后治疗组白介素10比较有统计学差异（P＜0．05）。结论中药通过调节IL－10的水平在IgA肾病的治疗中发挥其治疗作用。“,”s:ObjectiveToobservetheeffectofChineseherbalmedicineoninterleukin10inIgAnephropathy.Methods 30casesof IgA nephropathy were selected as treatment group,20 cases healthy people were selected as control group.Except hypertension patients trea-ted with antihypertensive ( angiotensin converting enzyme inhibitor and ( or) calcium antagonist) , the treatment groups were given TCM de-coction by syndrome differentiation treatment.No intervention measures were given to healthy control group.Flow cytometry was used to de-tect the levels of interleukin 10 in peripheral blood of treatment group and healthy control group and the results were compared.Results In-terleukin 10 of treatment group compared with healthy control group had significant difference (P<0.05);after the treatment, the treatment group of interleukin 10 compared with before treatment, there had significant differences (P<0.05) .Conclusion Traditional Chinese med-icine plays a therapeutic role in the treatment of IgA nephropathy by regulating the level of interleukin 10.