炎症与血管新生是两个相互联系,共同发展的病理过程。肿瘤、关节炎、慢性肠炎、新生血管性眼病等多种疾病中均涉及两者共同作用。寻找炎症与血管新生过程中的共同环节并给予干预具有重要临床意义。研究证实,血管生成素不仅是一类作用于内皮细胞的血管生长因子,还能够从多方面影响炎症的发生。这种双重功能使血管生成素成为极具潜力的抗炎、抗血管新生的共同靶点。 Inflammation and angiogenesis are two interrelated and common pathological processes. Tumors, arthritis, chronic enteritis, neovascular ophthalmopathy and other diseases involve both. It is of great clinical significance to find out the common links between inflammation and angiogenesis and to give interventions. Studies have shown that angiogenin is not only a class of vascular growth factor that acts on endothelial cells, but also affect the occurrence of inflammation in many ways. This dual function makes angiogenin a potential target for anti-inflammatory and anti-angiogenic targets.