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目的应用胞必佳和顺铂治疗恶性胞水,旨在观察临床疗效和毒副作用。方法采用细管行胸腔闭式持续引流,在胸水基本流净,肺复张基础上予以胞必佳600ug,顺铂40mg~80mg作胸腔内灌注一次性疗程。结果总有效率93.26%。毒副作用:胸内注药后出现胸痛、发热、恶心、呕吐等不良反应,经对症处理可以缓解。结论该疗法治疗恶性胸水疗效确切,毒副作用轻,安全方便,值得在临床上推广应用。
Objective To observe the clinical efficacy and toxic side effects of Cisplatin and Cisplatin in the treatment of malignant water. Methods Thoracic closed continuous drainage with thin tube line, in the basic flow of pleural effusion net, lung recruitment to be based on the cells will be best 600ug, cisplatin 40mg ~ 80mg for intrathoracic infusion of a course of treatment. The total effective rate of 93.26%. Side effects: chest pain, fever, nausea, vomiting and other adverse reactions, symptomatic treatment can be alleviated. Conclusion The treatment of malignant pleural effusion, the exact effect of toxic side effects, safe and convenient, it is worth in the clinical application.