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测定了瓜蒌薤白半夏汤对常压缺氧性肺动脉高压大鼠的 CAT、GSH～P_X 和 LPO 的影响。结果表明,瓜蒌薤白半夏汤能明显提高大鼠的 CAT、GSH—P_X 的活性和降低 LPO 的含量(P<0.01),说明本经方能够明显降低常压缺氧性肺动脉高压大鼠增强的脂质过氧化反应,纠正失衡的抗氧化物酶。
The effect of Gualou Baibai Xia Decoction on CAT, GSH~P_X and LPO of normobaric hypoxic pulmonary hypertension rats was determined. The results showed that guajibaibanxia decoction can significantly increase the activity of CAT and GSH-P_X and decrease the content of LPO in rats (P<0.01). This shows that this prescription can significantly reduce the enhancement of normobaric hypoxic pulmonary hypertension in rats. The lipid peroxidation reaction corrects the imbalance of the antioxidant enzymes.