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莨菪类药物治疗休克为我国医务人员所首创。东莨菪碱属于抗乙酰胆硷药物,有阻滞α及M、N受体的作用。其抗休克的疗效与应用如下: 1.有兴奋呼吸防治呼吸窘迫综合征的作用:作者另有著述,本文从略。2.改善微循环的作用:由于阻滞了α及M受体,使cGMP受到抑制,cAMP相应升高,从而减轻了氧耗,可供给β受体充分的ATP,阻断了α及M受体,减少了肾上素能的释放
Scopolamine treatment of shock for our medical staff first. Scopolamine is anti-acetylcholine drugs, block α and M, N receptor role. The anti-shock efficacy and application are as follows: 1. There is excitement respiratory prevention and treatment of respiratory distress syndrome role: the author of another article, this article omitted. 2. To improve the role of the microcirculation: due to the block of the α and M receptors, the cGMP was inhibited, cAMP corresponding increase, thereby reducing oxygen consumption, can provide adequate β receptor ATP, α and M blocked by Body, reducing the release of suprarenal energy