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目的观察比较慢性阻塞性肺疾病合并中度肺性脑病患者常规综合治疗基础上分别合用呼吸兴奋剂、无创B iPAP通气治疗、有创通气治疗三种治疗措施的疗效分析。方法中度肺性脑病患者30例使用呼吸兴奋剂为A组、30例使用无创B iPAP通气治疗为B组,30例使用有创通气治疗为C组,比较3组患者治疗疗效及住院日。结果无创B iPAP通气与有创通气对治疗中度肺性脑病疗效相近,均比呼吸兴奋剂药物治疗疗效显著,无创B iPAP通气治疗患者的住院日显著减少。结论无创B iPAP通气治疗对合适的慢性阻塞性肺疾病并中度肺性脑病患者是一种更有效、更缩短住院日、更少不良并发症出现的治疗措施。
Objective To compare the curative effects of three kinds of therapeutic measures on patients with chronic obstructive pulmonary disease and moderate pulmonary encephalopathy based on conventional comprehensive therapy combined with respiratory stimulant, noninvasive B iPAP ventilation and invasive ventilation. Methods Thirty patients with moderate pulmonary encephalopathy were treated with respiratory stimulant as group A, 30 as non-invasive B iPAP ventilation as group B and 30 as invasive gas therapy as group C, and the therapeutic effect and hospitalization day were compared among the three groups. Results The efficacy of noninvasive B iPAP ventilation and invasive ventilation in treating moderate pulmonary encephalopathy was similar to that of respiratory stimulant medication, and the hospitalization days of non-invasive B iPAP ventilation were significantly decreased. Conclusions Noninvasive B iPAP ventilation is a more effective and shorter hospitalization day for patients with COPD and moderate pulmonary encephalopathy.