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目的:研究肠易激综合征(IBS)患者直肠肛管运动功能。方法:观察了20例IBS患者和10例正常人直肠肛管压力及排便功能。结果:IBS便秘组直肠静息压显著低于正常对照组;肛管静息压明显高于对照组(P<0.05)。IBS腹泻组直肠静息压显著高于对照组;肛管静息压显著低于对照组(P<0.05)。模拟排便试验表明:IBS便秘组直肠感觉阈值及直肠最大耐受性明显增高;IBS腹泻组直肠感觉阈值及直肠最大耐受性均明显降低(P<0.05)。结论:IBS患者存在明显的肛管直肠动力学异常。
Objective: To study the rectal canal motor function in patients with irritable bowel syndrome (IBS). Methods: Rectal anal canal pressure and bowel function were examined in 20 IBS patients and 10 normal controls. Results: The resting pressure of rectum in IBS constipation group was significantly lower than that of normal control group. The resting pressure of anal canal was significantly higher than that of control group (P <0.05). IBS diarrhea rectal resting pressure was significantly higher than the control group; anal pressure was significantly lower than the control group (P <0.05). The simulated defecation test showed that the rectal sensation threshold and maximal rectal tolerance were significantly increased in IBS constipation group. The rectal sensation threshold and maximal rectal tolerance were significantly decreased in IBS diarrhea group (P <0.05). Conclusion: There is a significant abnormality of anorectal motility in patients with IBS.