论文部分内容阅读
目的:观察并讨论序贯疗法对根除幽门螺杆菌治疗失败后进行的补救治疗的临床疗效。方法:选取我院100例被确诊为幽门螺杆菌根治治疗失败的患者,随即进行根除幽门螺杆菌补救治疗,将所有患者随机分为实验组和对照组。实验组给予序贯疗法,对照组给予常规的四联疗法,疗程结束后4周,对两组分别进行14C尿素呼气试验检测幽门螺杆菌的根除情况并比较。结果:实验组幽门螺杆菌的根除率为94.8%,对照组幽门螺杆菌的根除率为72.5%,两组根除率差异显著,经过统计学计算两组的差异有统计学意义(p<0.05)。结论:序贯疗法作为对根除幽门螺杆菌失败的补救治疗,效果优于传统的四联法治疗,疗效显著,值得临床推广、应用。
OBJECTIVE: To observe and discuss the clinical effect of sequential therapy on the remedial treatment after the failure of eradication of Helicobacter pylori. Methods: One hundred patients in our hospital who were diagnosed as having failed Helicobacter pylori eradication treatment were enrolled. Eradication therapy of Helicobacter pylori was performed immediately. All patients were randomly divided into experimental group and control group. The experimental group was given sequential therapy, the control group was given conventional quadruple therapy, 4 weeks after the end of treatment, the two groups were 14 C urea breath test Helicobacter pylori eradication were compared and compared. Results: The eradication rate of Helicobacter pylori in the experimental group was 94.8%, while that in the control group was 72.5%. There was significant difference between the two groups in eradication rate (p <0.05) . Conclusion: Sequential therapy, as a remedy for the failure of eradication of Helicobacter pylori, is superior to traditional quadruple therapy in treating eradication of Helicobacter pylori, and has obvious curative effect. It is worthy of clinical promotion and application.