【摘 要】
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Objective:To explore the serum levels ofIL-32,MMP-9,PCT andCRP in patients with acute exacerbation of chronic obstructive pulmonary disease(AECOPD).Methods:A to
【机 构】
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Department of Respiratory Medicine, First Affiliated Hospital of Hebei North University, Zhangjiakou
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Objective:To explore the serum levels ofIL-32,MMP-9,PCT andCRP in patients with acute exacerbation of chronic obstructive pulmonary disease(AECOPD).Methods:A total of50 patients withAECOPD and45 cases with acute asthma attack admitted fromOctober2013 to August2014 were selected, and the serum levels ofIL-32,MMP-9,PCT andCRP were determined and compaed by usingDouble antibody sandwichEnzyme linked immunosorbent assay, immunofluorescence double antibody sandwich assay and immunoturbidimetry assay.Results:Serum levels ofIL-32,MMP-9,PCT andCRP were significantly higher inAECOPD group than acute asthma attack group(P<0.05).IL-32 andMMP-9 were negatively correlated with lung function.MMP-9 inAECOPD patients was increased more significantly.Conclusions:Serum levels ofIL-32 andMMP-9 were negatively correlated with lung function, and the worse the lung function is, the more significant the increase is.
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