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肺结核是一种慢性病,在治疗过程中由于种种原因而久治不愈,演变为复治者时有发生,且其中不少成为慢性传染源。据我们医院1979年在本地区部份农村调查中,复治病例中的慢性传染源为55.3%。这是一个严重的公共卫生问题。尤其是具有耐药性的细菌传染给别人后,就会造成原发性耐药,给新病人的治疗带来困难。因此,如何针对形成复治的原因,采取有效措施,减少和消灭复治病例,是结核病防治工作中一个很值得重视和进行探讨的课题。下面将我院从1978年10月~1979年12月所收集的104例复治肺结核病人的形成原因分析如下。一、资料来源与标准104例复治病人均为本院住院病人和本院在农村普查中发现的肺结核患者,他们均符合下列条件之一;(1)初治失败(规律化疗6个月痰菌仍阳性或病变恶化);(2)不规律化疗超过3个月;(3)Ⅲ组病人(即非活动性肺结核病人)病变恶化或取消登记后复发者。
Tuberculosis is a chronic disease that persists for a variety of reasons during the course of treatment. It has evolved into a retreat from time to time, and many of them have become chronic sources of infection. According to our hospital in some rural areas in the region in 1979, the rate of chronic infection in re-treatment cases was 55.3%. This is a serious public health issue. In particular, the transmission of drug-resistant bacteria to others can lead to primary drug resistance and cause difficulties in the treatment of new patients. Therefore, how to take effective measures to reduce and eliminate the cases of retreatment for the reason of the formation of retreatment is a topic worthy of attention and discussion in the prevention and treatment of tuberculosis. The following from our hospital from October 1978 to December 1979 collected 104 cases of re-treatment of pulmonary tuberculosis causes of the formation are as follows. First, the sources and standards 104 cases of re-treatment patients are hospitalized patients and our hospital in rural census found in tuberculosis patients, they meet one of the following conditions; (1) initial failure (regular chemotherapy 6 months sputum (2) Irregular chemotherapy for more than 3 months; (3) Patients in group III (ie, inactive pulmonary tuberculosis) who have deteriorated or have had their registration canceled.