高血压为心血管疾病并发症、死亡率增加的主要危险因素。鉴于高血压发生发展过程系多因素参与,包括肾储钠异常、神经激素过度激活、内皮功能不良、血管增生、系统炎症、纤溶功能降低及氧化应激增加等。因此全身多种生物指标异常,通过关键生物旁路,推测参与了显性高血压的发生。 Hypertension is a major risk factor for cardiovascular complications and increased mortality. In view of the occurrence and development of hypertension is a multifactorial factor involved, including abnormal renal sodium storage, excessive activation of neurohormones, endothelial dysfunction, vascular proliferation, systemic inflammation, decreased fibrinolysis and increased oxidative stress. Therefore, a variety of biological abnormalities throughout the body through the key biological bypass, presumably involved in the occurrence of overt hypertension.