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B淋巴细胞刺激因子(B lymphocyte stimulator,BLyS)是1999年发现的肿瘤坏死因子(tumor necrosis factor,TNF)家族的新成员,又称为THANK(TNF homologue that activates apoptosis,NF-κB and JNK)、TALL-1(TNF and ap0l related leukocyte expressed ligand 1)、BAFF(B cell activating factor belonging to the TNFfamily)等。