血栓弹力图指导主动脉夹层患者术后成分输血作用的探讨

来源 :临床血液学杂志(输血与检验) | 被引量 : 0次 | 上传用户:btlovers
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目的:探讨血栓弹力图(TEG)在指导主动脉夹层患者术后成分输血中的意义。方法:回顾性分析近2年成功进行手术治疗的50例主动脉夹层患者,比对术前和术后各项TEG检测参数及传统血常规和凝血项检测参数,并将术后各项参数与术后输注血浆、血小板和冷沉淀量进行相关性分析。结果:与术前相比,术后TEG参数中的R和K明显延长(P<0.01,P<0.05),α-Angle和MA明显减小(P<0.01),CI明显降低(P<0.01),术后凝血5项中的凝血酶原时间(PT)、激活部分凝血酶时间(APTT)、纤维蛋白原(FIB)、凝血酶时间(TT)明显延长(P<0.01),血小板计数(PLT)计数明显降低(P<0.01)。术后血浆输注量与各项凝血参数均无相关性,血小板输注量与MA和PLT计数有显著相关性(P<0.01,P<0.05),冷沉淀输注量与K值、α-Angle和APTT有显著相关性(P<0.01,P<0.01,P<0.05)。结论:TEG可以提示主动脉夹层手术患者术后的凝血功能障碍,MA值可以指导血小板的输注,α-Angle和K值可以作为术后冷沉淀输注的重要参考,并应注意R值在指导血浆输注中的意义。 Objective: To investigate the significance of thrombus elastography (TEG) in guiding blood transfusion after operation in patients with aortic dissection. Methods: A total of 50 patients with aortic dissection who underwent successful surgical treatment in recent 2 years were retrospectively analyzed. TEG detection parameters, conventional blood routine and coagulation parameters were compared before and after surgery. Parameters of postoperative Postoperative infusion of plasma, platelet and cryoprecipitate for correlation analysis. Results: Compared with preoperative, R and K in TEG parameters were significantly prolonged (P <0.01, P <0.05), α-Angle and MA significantly decreased (P <0.01) ), PTT, APTT, fibrinogen (FIB) and thromboplastin time (TT) were significantly prolonged (P <0.01), and platelet count PLT) count was significantly lower (P <0.01). There was no correlation between postoperative plasma transfusion volume and coagulation parameters. Platelet transfusion volume was significantly correlated with MA and PLT count (P <0.01, P <0.05) There was a significant correlation between Angle and APTT (P <0.01, P <0.01, P <0.05). Conclusion: TEG can prompt coagulation dysfunction in patients with aortic dissection, MA value can guide platelet transfusion, α-Angle and K value can be used as an important reference for postoperative cryoprecipitate infusion, and should pay attention to R value in Guide the meaning of plasma infusion.
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