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用高效液相色谱法测定了单纯双氯灭痛、双氯灭痛β－环糊精包合物（共沉淀法、冷冻干燥法）三种样品在家兔体内的血浓度，在ＩＢＭ计算机上求算药动学参数。相对生物利用度分别为８４７．５１８％（共沉淀法），８７８．５２３％（冷冻干燥法）．双氯灭痛在体内的分布呈一室模型。
The blood concentrations of three samples of diclofenac and diclofenac-β-cyclodextrin inclusion complexes (coprecipitation and freeze-drying) in rabbits were determined by HPLC. The pharmacokinetic parameters were calculated by IBM computer . Relative bioavailability were 847.518% (coprecipitation method), 878.523% (freeze-drying method). Diclofenac is distributed in the body in a one-compartment model.