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目的探讨原发性CD30+间变大细胞淋巴瘤的组织学特点及免疫组化特征。方法运用组织形态学、免疫组化方法研究1例发生面部的间变性大细胞淋巴瘤并结合文献进行复习。结果间变大细胞淋巴瘤其形态学表现为多样性,免疫组化显示,CD30阳性、CD3阳性、CD45RO阳性、CD43阳性、vimentin阳性。结论原发性CD30+间变大细胞淋巴瘤临床罕见,其形态学和免疫组化表型有一定的特殊性,有必要与其他类型的淋巴瘤鉴别。
Objective To investigate the histological features and immunohistochemical features of primary CD30 + mesenchymal lymphoma. Methods One case of anaplastic large cell lymphoma was studied by histomorphology and immunohistochemistry and reviewed with literature. Results Morphology of large, variant cell lymphoma showed diversity. Immunohistochemistry showed that CD30 was positive, CD3 was positive, CD45RO was positive, CD43 was positive and vimentin was positive. Conclusions Primary CD30 + mesenchymal lymphoma is rare in clinical practice. Its morphological and immunohistochemical phenotype has some particularities. It is necessary to identify with other types of lymphomas.