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目的了解某高校退休教职工脂肪肝患病率及其影响因素,为预防脂肪肝提供依据。方法 2013年将广州市某高校退休教职工健康检查的1 081人作为分析对象,分析其脂肪肝患病情况及其血清胆固醇(TC)、甘油三酯(TG)、低密度脂蛋白胆固醇(LDL-C)、高密度脂蛋白胆固醇(HDL-C)、血尿酸(UA)、血糖(GLU)和丙氨酸氨基转移酶(ALT)的水平,且与非脂肪肝人群进行比较分析。结果退休教职工脂肪肝检出率为28.86%(312/1 081)。患脂肪肝组的TG、UA、GLU和ALT的水平高于非患脂肪肝组,其中TG、UA、GLU差异有统计学意义(P<0.01);HDL-C的水平低于非患脂肪肝组,差异有统计学意义(P<0.01)。结论受检人群脂肪肝检出率偏高;血脂异常、高尿酸血症、糖尿病与脂肪肝有密切关系;脂肪肝患者可表现ALT水平升高,应引起重视。
Objective To understand the prevalence and influencing factors of fatty liver in retired teaching staff in a university and provide the basis for preventing fatty liver. Methods A total of 1 081 medical examinations of retired teaching staff in a certain university in Guangzhou were analyzed in 2013. The prevalence of fatty liver and the serum TC, TG, LDL C, HDL-C, UA, GLU and ALT were measured and compared with non-fatty liver patients. Results The detection rate of fatty liver in retired staff was 28.86% (312/1 081). The levels of TG, UA, GLU and ALT in fatty liver group were higher than those in non-fatty liver group (P <0.01), while the levels of HDL-C were lower than those in non-fatty liver Group, the difference was statistically significant (P <0.01). Conclusions The detection rate of fatty liver in the tested subjects is high. The dyslipidemia, hyperuricemia and diabetes mellitus are closely related to fatty liver. Fatty liver patients may show elevated ALT level, which should be paid more attention.