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目的:初步探讨成年人脊柱裂并发脑积水的发病率及相关问题。方法:使用磁共振(MRI)成像技术采集46例成年人脊柱裂患者的颅部解剖像,扫描参数为TR/TE 3 900 ms/15 ms,层数42层,层厚3 mm,视窗20 cm×20 cm,矩阵512×512。结果:46例患者中,20例发现不同程度的脑积水,占本组脊柱裂患者的43.5%;MRI成像可见侧脑室明显扩大,基底节、下丘脑严重萎缩。结论:国内脊柱裂患者并发脑积水的发生率远低于西方文献报道(约为85%);其并发脑积水的机制尚不明确,所引起的一系列综合征需引起临床重视。更精确的结果尚需更大样本的深入研究。
Objective: To investigate the incidence and related problems of hydrocephalus in adults with spina bifida complicated. Methods: Magnetic resonance imaging (MRI) was used to collect craniofacial anatomy of 46 adult spina bifida patients. The scanning parameters were TR / TE 3 900 ms / 15 ms, layer number 42, layer thickness 3 mm and window 20 cm × 20 cm, matrix 512 × 512. Results: Of the 46 patients, 20 cases found different degrees of hydrocephalus, accounting for 43.5% of the patients with spina bifida in this group. MRI showed that the lateral ventricle was significantly enlarged and the basal ganglia and hypothalamus atrophied. Conclusions: The incidence of hydrocephalus complicated by spina bifida in China is much lower than that reported in the western literature (about 85%). The mechanism of hydrocephalus complicated by hydrocephalus is not yet clear. A series of syndromes caused by this syndrome need clinical attention. More accurate results still need a larger sample of in-depth study.