在治疗无症状的轻度高血压时,主要应考虑选择一种不增加症状的药物。利尿药和β受体阻滞药仍是常用的首选药物,但它们的临床地位正在受到较新药物的挑战。利尿药小剂量噻嗪类(例如每晨口服苄氟噻嗪2.5mg或环戊噻嗪0.5mg)价格低廉,对于多数患者使用方便,很少产生有症状的副反应。已经确定,年老患者用利尿药比年轻患者较易奏效。应按患者年龄选择药物,而不是根据高血压机制(可能涉及肾素类型)选药。对于伴发高血压和充血性心力衰竭的患者,由于利尿药可同时治疗这两种疾病,因而 In the treatment of asymptomatic mild hypertension, the main consideration should be to choose a drug that does not increase the symptoms. Diuretics and beta-blockers are still the preferred first-line drugs, but their clinical status is being challenged by newer drugs. Diuretics Low-dose thiazides (eg, 2.5 mg of bendroflumethiazide or 0.5 mg of cyclopentothiazine per morning) are inexpensive and are easy to use for the majority of patients with few symptomatic side effects. It has been determined that diuretics in older patients are more effective than younger patients. Drugs should be chosen on a patient-by-patient basis and not on the basis of the mechanism of hypertension (which may involve renin types). For patients with concomitant hypertension and congestive heart failure, diuretics can treat both diseases at the same time