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目的:评价筛查男性腹主动脉瘤能否减少其死亡率。设计:基于人群的随机对照试验,行超声检查,分析患者年龄标化死亡率。地点:澳洲西部,基于社区的筛查项目。参加者:65-83岁的男性41000人,随机分为干预组和对照组。干预:邀请社区人群参加超声检查。主要结果衡量指标:进行此项干预后5年内腹主动脉瘤患者的死亡率。结果:被筛查者的校正反应为70%。直径≥30mm的腹主动脉瘤自然患病率为7.2%,≥55mm的为0.5%,干预组行选择性腹主动脉瘤手术的男性患者是对照组的2倍(107比54,P=0.002,x2检验)。在筛查至随访结束期间,
PURPOSE: To evaluate whether screening of male abdominal aortic aneurysms can reduce their mortality. Design: A population-based randomized controlled trial, performing an ultrasound examination and analyzing patient age-standardized mortality. Location: Western Australia, community-based screening program. Participants: 41000 men 65-83 years old, were randomly divided into intervention group and control group. Intervention: Invite community members to participate in the ultrasound examination. Main Outcome Measures: Mortality in patients with abdominal aortic aneurysm within 5 years of this intervention. Results: The screening response was 70%. The natural prevalence of abdominal aortic aneurysm with a diameter ≥30mm was 7.2% and 0.5% ≥55mm. The male patients in the intervention group who underwent selective abdominal aortic aneurysm operation were twice that of the control group (107 vs 54 , P = 0.002, x2 test). During the screening to the end of follow-up,