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目的探讨维持性血液透析中不同血液净化方式对残余肾功能的影响。方法选取2008年1月至2010年3月收治的维持性血液透析有残余肾功能患者146例,依据血液净化方式分为高通量透析(HFHD)组、低通量透析(LF-HD)组、血液透析联合血液灌注(HD+HP)组,观察各组残余肾功能。结果各组血液透析前残余肾功能比较差异无统计学意义。HFHD组、HD+HP组血液透析6、8个月时与LFHD组残余肾功能比较差异有统计学意义(P<0.05)。结论对于维持性血液透析血液净化方式非常重要,可以有效地减缓残余肾功能恶化,最大限度保护残余肾功能,改善患者生活质量。
Objective To investigate the effect of different blood purification methods on residual renal function in maintenance hemodialysis. Methods A total of 146 patients with residual renal function in maintenance hemodialysis who were admitted from January 2008 to March 2010 were divided into high-flux dialysis (HFHD) group, low-flux dialysis (LF-HD) group , Hemodialysis combined with blood perfusion (HD + HP) group, observe the residual renal function in each group. Results There was no significant difference in residual renal function before hemodialysis in each group. There were significant differences in residual renal function between HFHD group and HD + HP group and LFHD group at 6 and 8 months (P <0.05). Conclusions The maintenance of hemodialysis blood purification is very important, can effectively reduce the deterioration of residual renal function, to maximize the protection of residual renal function, improve patient quality of life.