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目的了解剖宫产患者围术期抗菌药物使用情况,为促进抗菌药物合理使用提供参考。方法回顾分析2013年6~8月435例剖宫产病历,对患者应用抗菌药物种类及频度、给药方法、用药天数、联合用药等资料进行统计分析。结果 435例剖宫产患者抗菌药物使用率100%,均为术前0.5~1h静脉给药;术前术后用药一致176例(40.46%),术后换药259例(59.54%),其中有指征换药238例(91.89%),联合用药84例(19.31%);用药时间≤48h、>48h、≥72h分别为402例(92.41%)、9例(2.07%)、24例(5.52%);用药频次居前三位为头孢唑林、头孢呋辛、甲硝唑。结论剖宫产患者抗菌药物预防用药时机、品种选择比较合理,但抗菌药物的疗程、术后换药、联合用药方面仍存在不规范。
Objective To understand the use of antimicrobial agents during cesarean section in perioperative period, and to provide reference for the rational use of antimicrobial agents. Methods A retrospective analysis of 435 cases of cesarean section from June to August in 2013 was conducted to analyze the types and frequency of antimicrobial agents, the method of administration, the days of treatment and the combination of drugs. Results 435 cases of cesarean section patients with antibacterial drug utilization rate of 100%, were preoperative 0.5 ~ 1h intravenous administration; medication consistent before and after 176 cases (40.46%), postoperative dressing change in 259 cases (59.54%), There were 238 cases (91.89%) with indications for drug replacement and 84 cases (19.31%) with drug combination. The medication time was 48 h,> 48 h, and ≥72 h respectively, 402 cases were 92.41%, 9 cases were 2.07% 5.52%). The top three drugs were cefazolin, cefuroxime and metronidazole. Conclusion Cesarean section in patients with antimicrobial agents to prevent the timing of medication, the choice of species is more reasonable, but the course of antimicrobial drugs, postoperative dressing, combination of drugs there are still non-standard.