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对60例婴幼儿急性肺炎中29例采用精制α型人白细胞干扰素加抗生素治疗(治疗组,其中病毒性肺炎15例),以单用抗生素治疗的31例作对照(其中病毒性肺炎16例)。结果显示,病毒性肺炎治疗组较对照组的临床表现消失时间缩短1.4～2.8天,临床治愈及痊愈时间分别平均缩短1.9天和1.5天。两组间差异有显著性。干扰素治疗前后,淋巴细胞绝对值、T细胞及其亚类以及血清免疫球蛋白含量差异均无显著性,但OKT_3比值略有上升,OKT_3略有下降趋势。
Twenty-nine infants and young children with acute pneumonia were treated with purified alpha interferon plus antibiotics (treatment group, 15 cases of viral pneumonia) and 31 cases treated with antibiotics alone (including 16 cases of viral pneumonia ). The results showed that the viral pneumonia treatment group than the control group, the disappearance of the clinical manifestations of time to shorten 1.4 to 2.8 days, clinical cure and cure time were shortened by an average of 1.9 days and 1.5 days. The difference between the two groups was significant. Before and after interferon treatment, the absolute value of lymphocytes, T cells and their subclasses and serum immunoglobulin content was no significant difference, but OKT_3 ratio increased slightly, OKT_3 slightly downward trend.