新型材料在脉冲释药系统中的应用进展

来源 :中国医药工业杂志 | 被引量 : 0次 | 上传用户:xueluowushengkk
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脉冲释药系统具有使药物经预定的时滞后快速或缓控释释放的特点。释药时滞的控制一是依靠外界刺激的触发,另一是依靠制剂本身设定的程序。目前,设计以外界因素刺激来触发脉冲释药的研究日益增多。在查阅近年文献基础上,综述了酶敏感、pH敏感、温度敏感及双敏感等新材料在具有脉冲特性的口服、膜剂、水凝胶和注射剂等给药系统中的应用进展。
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